Urate-ribonucleotide phosphorylase
In enzymology, an urate-ribonucleotide phosphorylase (EC 2.4.2.16) is an enzyme that catalyzes the chemical reaction
- urate D-ribonucleotide + phosphate
urate + alpha-D-ribose 1-phosphate
Thus, the two substrates of this enzyme are urate D-ribonucleotide and phosphate, whereas its two products are urate and alpha-D-ribose 1-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is urate-ribonucleotide:phosphate alpha-D-ribosyltransferase. Other names in common use include UAR phosphorylase, and urate-ribonucleotide:phosphate D-ribosyltransferase. This enzyme participates in purine metabolism.
References
- Laster L and Blair A (1963). "An intestinal phosphorylase for uric acid ribonucleoside". J. Biol. Chem. 238: 3348–3357. PMID 14085385.
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