4-phytase

Thus, the two substrates of this enzyme are myo-inositol hexakisphosphate and H₂O, whereas its two products are 1D-myo-inositol 1,2,3,4,5-pentakisphosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is myo-inositol-hexakisphosphate 6-phosphohydrolase. Other names in common use include 6-phytase (name based on 1L-numbering system and not 1D-numbering), phytase, and phytate 6-phosphatase. This enzyme participates in inositol phosphate metabolism.

References

Johnson LF, Tate ME (1969). "The structure of myo-inositol pentaphosphates". Ann. N. Y. Acad. Sci. 165 (2): 526–32. doi:10.1111/j.1749-6632.1970.tb56420.x. PMID 4310376.
Tomlinson RV and Ballou CE (1962). "Myoinositol polyphosphate intermediates in the dephosphorylation of phytic acid by phytase". Biochemistry 1: 166–171. doi:10.1021/bi00907a025. PMID 13921788.
Lim PE, Tate ME (1973). "The phytases. II. Properties of phytase fractions F 1 and F 2 from wheat bran and the myoinositol phosphates produced by fraction F 2". Biochim. Biophys. Acta 302 (2): 316–28. doi:10.1016/0005-2744(73)90160-5. PMID 4349266.
Cosgrove DJ. "Inositol Phosphates: Their Chemistry, Biochemistry, and Physiology, Elsevier, Amsterdam, 1980".

Hydrolase: esterases (EC 3.1)

3.1.1: Carboxylic
ester hydrolases

Lipase

Phospholipase
- A1
- A2
- B

3.1.2: Thioesterase

3.1.3: Phosphatase

3.1.4: Phosphodiesterase

3.1.6: Sulfatase

Nuclease (includes
deoxyribonuclease and
ribonuclease)

3.1.11-16: Exonuclease

Exodeoxyribonuclease	RecBCD

Exoribonuclease	Oligonucleotidase

3.1.21-31: Endonuclease

Endodeoxyribonuclease	Deoxyribonuclease I Deoxyribonuclease II Deoxyribonuclease IV Restriction enzyme UvrABC endonuclease

Endoribonuclease	RNase III RNase H 1 2A 2B 2C RNase P RNase A 1 2 3 4/5 RNase T1 RNA-induced silencing complex

either deoxy- or ribo-	Aspergillus nuclease S1 Micrococcal nuclease

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

This article is issued from Wikipedia - version of the Thursday, March 31, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.