Aspergillus deoxyribonuclease K1

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Aspergillus deoxyribonuclease K1 (EC 3.1.22.2, Aspergillus DNase K1) is an enzyme.^[1]^[2] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products

This enzyme has preference for single-stranded DNA.

References

↑ Kato, M. and Ikeda, Y. On the deoxyribonucleases, K (1968). "1 and K2, isolated from mycelia of Aspergillus oryzae. I. Isolation and purification of DNases K1 and K2". J. Biochem. (Tokyo) 64: 321–328. PMID 4303413.
↑ Shishido, K., Kato, M. and Ikeda, Y. (1968). "Isolation of thymidylic acid-rich fragments from double-stranded deoxyribonucleic acids". J. Biochem. (Tokyo) 65: 479–481.

External links

Aspergillus deoxyribonuclease K1 at the US National Library of Medicine Medical Subject Headings (MeSH)

Hydrolase: esterases (EC 3.1)

3.1.1: Carboxylic
ester hydrolases

Lipase

Phospholipase
- A1
- A2
- B

3.1.2: Thioesterase

3.1.3: Phosphatase

3.1.4: Phosphodiesterase

3.1.6: Sulfatase

Nuclease (includes
deoxyribonuclease and
ribonuclease)

3.1.11-16: Exonuclease

Exodeoxyribonuclease	RecBCD

Exoribonuclease	Oligonucleotidase

3.1.21-31: Endonuclease

Endodeoxyribonuclease	Deoxyribonuclease I Deoxyribonuclease II Deoxyribonuclease IV Restriction enzyme UvrABC endonuclease

Endoribonuclease	RNase III RNase H 1 2A 2B 2C RNase P RNase A 1 2 3 4/5 RNase T1 RNA-induced silencing complex

either deoxy- or ribo-	Aspergillus nuclease S1 Micrococcal nuclease

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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