| Weekday programming |
| ET | Program | Retransmitted channel | Hosts | Description |
| 00:00 | Capital Connection | CNBC World (from CNBC Asia) | Sri Jegarajah and Nancy Hulgrave | The bridge between the Asian and European trading days | Live |
| 01:00 | Squawk Box Europe | CNBC World (from CNBC Europe) | Geoff Cutmore, Steve Sedgwick, Karen Tso | Derived from CNBC's Squawk Box |
| 04:00 | Worldwide Exchange | CNBC | Wilfred Frost, Susan Li | CNBC's global business programme |
| 06:00 | Squawk Box | Joe Kernen, Rebecca Quick and Andrew Ross Sorkin | Provides a mix of business news and commentary |
| 09:00 | Squawk on the Street | Carl Quintanilla, David Faber, Jim Cramer, Simon Hobbs and Sara Eisen | Focuses on real-time market coverage at the start of the trading day |
| 11:00 | Squawk Alley | Carl Quintanilla, Kayla Tausche and Jon Fortt | Covering the intersection between Wall Street and the technology world |
| 12:00 | Fast Money Half Time Report | Scott Wapner | A fast-paced discussion of the day's market action at the midpoint of the trading day |
| 13:00 | Power Lunch | Tyler Mathisen and Amanda Drury, and Brian Sullivan and Melissa Lee | Examines the companies, people, and trends influencing Wall Street |
| 15:00 | Closing Bell | Kelly Evans and Bill Griffeth | Covers the close of the trading day |
| 17:00 | Fast Money | Melissa Lee (host), Pete Najarian, Guy Adami, Tim Seymour and Karen Finerman (panelists) | A fast-paced discussion of the day's market action |
| 18:00 | Mad Money | Jim Cramer | A fast-paced show offering stock advice to callers |
| 19:00 | Late Night with Jimmy Fallon | Jimmy Fallon | Talk show | Rerun from 00:35 on NBC |
| N/A (EST) / 20:00 (EDT) | Asia Squawk Box | CNBC World (from CNBC Asia) | Bernard Lo | Derived from CNBC's Squawk Box | Live |
| 21:00 (EST) / 22:00 (EDT) | Street Signs | Martin Soong and Oriel Morrison | Derived from CNBC's former Street Signs programme |
| 23:00 | Mad Money | CNBC | Jim Cramer | Fast-paced show offering stock advice to callers | Rerun from 18:00 |
