Collagen, type XIV, alpha 1

Collagen, type XIV, alpha 1
Identifiers
Symbols	COL14A1 ; UND
External IDs	OMIM: 120324 MGI: 1341272 HomoloGene: 18741 GeneCards: COL14A1 Gene
Gene ontology Molecular function • extracellular matrix structural constituent • collagen binding • protein binding, bridging • poly(A) RNA binding Cellular component • extracellular region • proteinaceous extracellular matrix • collagen trimer • collagen type XIV trimer • interstitial matrix • extracellular space • endoplasmic reticulum lumen • extracellular matrix • extracellular exosome Biological process • ventricular cardiac muscle tissue development • single organismal cell-cell adhesion • extracellular matrix disassembly • extracellular matrix organization • collagen fibril organization • collagen catabolic process • homeostasis of number of cells within a tissue • regulation of cell growth involved in cardiac muscle cell development Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7373	12818
Ensembl	ENSG00000187955	ENSMUSG00000022371
UniProt	Q05707	Q80X19
RefSeq (mRNA)	NM_021110	NM_181277
RefSeq (protein)	NP_066933	NP_851794
Location (UCSC)	Chr 8: 120.06 – 120.37 Mb	Chr 15: 55.31 – 55.52 Mb
PubMed search

Collagen alpha-1(XIV) chain is a protein that in humans is encoded by the COL14A1 gene.^[1][2][3]

References

1. Just M, Herbst H, Hummel M, Durkop H, Tripier D, Stein H, Schuppan D (Oct 1991). "Undulin is a novel member of the fibronectin-tenascin family of extracellular matrix glycoproteins". J Biol Chem 266 (26): 17326–32. PMID 1716629.
2. Bauer M, Dieterich W, Ehnis T, Schuppan D (Jan 1998). "Complete primary structure of human collagen type XIV (undulin)". Biochim Biophys Acta 1354 (3): 183–8. doi:10.1016/S0167-4781(97)00131-0. PMID 9427527.
3. "Entrez Gene: COL14A1 collagen, type XIV, alpha 1 (undulin)".

Further reading

• Schuppan D, Cantaluppi MC, Becker J; et al. (1990). "Undulin, an extracellular matrix glycoprotein associated with collagen fibrils.". J. Biol. Chem. 265 (15): 8823–32. PMID 2187872.
• Schnittger S, Herbst H, Schuppan D; et al. (1995). "Localization of the undulin gene (UND) to human chromosome band 8q23.". Cytogenet. Cell Genet. 68 (3-4): 233–4. doi:10.1159/000133920. PMID 7842743.
• Casini A, Ceni E, Salzano R; et al. (1994). "Regulation of undulin synthesis and gene expression in human fat-storing cells by acetaldehyde and transforming growth factor-beta 1: comparison with fibronectin.". Biochem. Biophys. Res. Commun. 199 (2): 1019–26. doi:10.1006/bbrc.1994.1331. PMID 8135774.
• Tono-Oka S, Tanase S, Miike T, Tanaka H (1996). "Transient expression of collagen type XIV during muscle development and its reappearance after denervation and degeneration.". J. Histochem. Cytochem. 44 (8): 907–18. doi:10.1177/44.8.8756762. PMID 8756762.
• Ehnis T, Dieterich W, Bauer M; et al. (1997). "A chondroitin/dermatan sulfate form of CD44 is a receptor for collagen XIV (undulin).". Exp. Cell Res. 229 (2): 388–97. doi:10.1006/excr.1996.0384. PMID 8986622.
• Göpel C, Schultka R, Schuppan D (1997). "[Age-dependent distribution of collagen and glycoproteins in the blood vessels of the human uterine tube]". Ann. Anat. 179 (1): 83–8. PMID 9092299.
• Ehnis T, Dieterich W, Bauer M; et al. (1997). "Localization of a binding site for the proteoglycan decorin on collagen XIV (undulin).". J. Biol. Chem. 272 (33): 20414–9. doi:10.1074/jbc.272.33.20414. PMID 9252349.
• Imhof M, Trueb B (1999). "Comparative cytogenetic mapping of COL14A1, the gene for human and mouse collagen XIV.". Cytogenet. Cell Genet. 84 (3-4): 217–9. doi:10.1159/000015262. PMID 10393435.
• Fukushima M, Hirano S, Tanaka H (2000). "Dorsoventral differential distribution of collagen type XIV around the spinal cord is regulated by the ectoderm.". Dev. Growth Differ. 41 (6): 751–8. doi:10.1046/j.1440-169x.1999.00472.x. PMID 10646805.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerecke DR, Meng X, Liu B, Birk DE (2004). "Complete primary structure and genomic organization of the mouse Col14a1 gene.". Matrix Biol. 22 (7): 595–601. doi:10.1016/j.matbio.2003.11.005. PMID 15065570.
• Brandenberger R, Wei H, Zhang S; et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Thierry L, Geiser AS, Hansen A; et al. (2005). "Collagen types XII and XIV are present in basement membrane zones during human embryonic development.". J. Mol. Histol. 35 (8-9): 803–10. doi:10.1007/s10735-004-1132-y. PMID 15609093.
• Ruehl M, Erben U, Schuppan D; et al. (2006). "The elongated first fibronectin type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes.". J. Biol. Chem. 280 (46): 38537–43. doi:10.1074/jbc.M502210200. PMID 16129687.
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Nusbaum C, Mikkelsen TS, Zody MC; et al. (2006). "DNA sequence and analysis of human chromosome 8.". Nature 439 (7074): 331–5. doi:10.1038/nature04406. PMID 16421571.