Collagen, type VI, alpha 5

Collagen, type VI, alpha 5
Identifiers
Symbols	COL6A5 ; COL29A1; VWA4
External IDs	OMIM: 611916 HomoloGene: 122792 GeneCards: COL6A5 Gene
Gene ontology Molecular function • protein binding Cellular component • extracellular region • proteinaceous extracellular matrix • collagen trimer • extracellular matrix Biological process • cell adhesion • extracellular matrix disassembly • extracellular matrix organization • collagen catabolic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	256076	665033
Ensembl	ENSG00000172752	ENSMUSG00000091345
UniProt	A8TX70	A6H584
RefSeq (mRNA)	NM_001278298	NM_001167923.1
RefSeq (protein)	NP_001265227	NP_001161395.1
Location (UCSC)	Chr 3: 130.35 – 130.48 Mb	Chr 9: 105.84 – 105.98 Mb
PubMed search

Collagen alpha-5(VI) chain also known as von Willebrand factor A domain-containing protein 4 is a protein that in humans is encoded by the COL6A5 gene.

COL6A5 is a part of the Collagen VI gene family which produce collagen components for the Extracellular matrix of most connective tissues.^[1] In the human genome, part of the collagen VI family is located on chromosome 3q in order of COL6A4, COL6A5, COL6A6.^[1] Transcription of COL6A5 only occurs in skin, lung, testis, colon, and small intestine cells.^[1]

References

1. Fitzgerald J, Holden P, Hansen U (2013). "The expanded collagen VI family: new chains and new questions". Connective Tissue Research 54 (6): 345–50. doi:10.3109/03008207.2013.822865. PMID 23869615.