Type-V collagen

Type-V collagen is a form of fibrillar^[1] collagen associated with classical Ehlers-Danlos syndrome.^[2]

Autoimmunity against type V collagen is associated with lung transplant failure.^[3][4]

Genes

• COL5A1, COL5A2, COL5A3

References

1. Wenstrup RJ, Florer JB, Brunskill EW, Bell SM, Chervoneva I, Birk DE (2004). "Type V collagen controls the initiation of collagen fibril assembly". J. Biol. Chem. 279 (51): 53331–7. doi:10.1074/jbc.M409622200. PMID 15383546.
2. Malfait, F; Wenstrup, R; De Paepe, A; Pagon, RA; Adam, MP; Bird, TD; Dolan, CR; Fong, CT; Smith, RJH; Stephens, K (1993). "Ehlers-Danlos Syndrome, Classic Type". PMID 20301422. Cite uses deprecated parameter |coauthors= (help)
3. Haque, MA; Mizobuchi, T; Yasufuku, K; Fujisawa, T; Brutkiewicz, RR; Zheng, Y; Woods, K; Smith, GN; Cummings, OW; Heidler, KM; Blum, JS; Wilkes, DS (Aug 1, 2002). "Evidence for immune responses to a self-antigen in lung transplantation: role of type V collagen-specific T cells in the pathogenesis of lung allograft rejection.". Journal of immunology (Baltimore, Md. : 1950) 169 (3): 1542–9. doi:10.4049/jimmunol.169.3.1542. PMID 12133982.
4. Iwata, T; Philipovskiy, A; Fisher, AJ; Presson RG, Jr; Chiyo, M; Lee, J; Mickler, E; Smith, GN; Petrache, I; Brand, DB; Burlingham, WJ; Gopalakrishnan, B; Greenspan, DS; Christie, JD; Wilkes, DS (Oct 15, 2008). "Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction.". Journal of immunology (Baltimore, Md. : 1950) 181 (8): 5738–47. doi:10.4049/jimmunol.181.8.5738. PMC 2997998. PMID 18832733. Cite uses deprecated parameter |coauthors= (help)

External links

• Collagen Type V at the US National Library of Medicine Medical Subject Headings (MeSH)