EHNA
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Systematic (IUPAC) name | |
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3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride | |
Identifiers | |
CAS Number | 59262-86-1 |
PubChem | CID 359137 |
ChEMBL |
CHEMBL50378 ![]() |
Chemical data | |
Formula | C14H24ClN5O |
Molar mass | 313.826 g/mol |
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EHNA (erythro-9-(2-hydroxy-3-nonyl)adenine) is a potent adenosine deaminase inhibitor,[1] which also acts as a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type 2 (PDE2).[2][3]
References
- ↑ "Sigma Aldrich". Retrieved 16 January 2013.
- ↑ Podzuweit, T; Nennstiel, P; Muller, A (1995). "Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine". Cell Signal 7 (7): 733–8. doi:10.1016/0898-6568(95)00042-N. PMID 8519602.
- ↑ Méry, PF; Pavoine, C; Pecker, F; Fischmeister, R (1995). "Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes". Mol Pharmacol 48 (1): 121–130. PMID 7623766.
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