EHNA

EHNA
Systematic (IUPAC) name
3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride
Identifiers
CAS Number 59262-86-1
PubChem CID 359137
ChEMBL CHEMBL50378 YesY
Chemical data
Formula C14H24ClN5O
Molar mass 313.826 g/mol
  (verify)

EHNA (erythro-9-(2-hydroxy-3-nonyl)adenine) is a potent adenosine deaminase inhibitor,[1] which also acts as a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type 2 (PDE2).[2][3]

References

  1. "Sigma Aldrich". Retrieved 16 January 2013.
  2. Podzuweit, T; Nennstiel, P; Muller, A (1995). "Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine". Cell Signal 7 (7): 733–8. doi:10.1016/0898-6568(95)00042-N. PMID 8519602.
  3. Méry, PF; Pavoine, C; Pecker, F; Fischmeister, R (1995). "Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes". Mol Pharmacol 48 (1): 121–130. PMID 7623766.


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