HLA-B*82

major histocompatibility complex (human), class I, B82
Alleles	B*8201
Structure (See HLA-B)
Symbol(s)	HLA-B
Locus	chr.6 6p21.31

HLA-B*82 (B*82) is an HLA-B allele-group. There is no current useful serotyping for HLA-B*82 gene products.^[1] B*8201 was first identified by sequence analysis and appears to be derived by gene conversion between B*5602 and another HLA class I allele.,^[2] later B*8202 was identified in a caucasian and was suggested to be ancestral to B*8201, as product between gene conversion of B*5602 allele and B*4501 allele. B*82 is more common in East Africa, Kenya and Sudan, the frequency of B*8201 is found in the peoples to the west, sporadically in Central and West Africa, B*8202 is found in Sudan and Saudi Arabia.^[3]

Serotype

B82 serotype recognition of Some HLA B*82 allele-group gene products^[4]

B*82	B82	other	Sample
allele	%	%	size (N)
*8201	3	79	146

Allele frequencies

HLA B*8201 frequencies

		freq
ref.	Population	(%)
[5]	Luo (Kenya)	1.9
[5]	Guinea Bissau	0.8
[5]	Natal Zulu (S. Africa)	0.5
[5]	Beti (Cameroon)	0.3
[5]	Kenya	0.3
[5]	Kampala (Uganda)	0.3
[5]	Nandi (Kenya)	0.2
'
HLA B**8202 frequencies
[5]	Sudanese	2.5
[5]	Kenya	0.7
[5]	Guraiat and Hail (Saudi Arabia)	0.2

References

1. Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
2. Hurley CK, Steiner N, Hoyer RJ, et al. (1996). "Novel HLA-B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types". Tissue Antigens 47 (3): 179–87. doi:10.1111/j.1399-0039.1996.tb02538.x. PMID 8740766.
3. Cox ST, Hossain E, McWhinnie A, Prokupek B, Madrigal JA, Little AM (2000). "HLA-B*8202 identified in a Caucasoid potential bone marrow donor". Tissue Antigens 56 (2): 188–91. doi:10.1034/j.1399-0039.2000.560216.x. PMID 11019925.
4. derived from IMGT/HLA
5. Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)