HLA-B70

HLA-B (alpha)-β2MG with bound peptide
major histocompatibility complex (human), class I, B70
Alleles *1503, *1509, *1510,
*1518, *1529, *1537
Structure (See HLA-B)
Shared data
Locus chr.6 6p21.31

HLA-B70 (B70) is an HLA-B serotype. The serotype identifies certain B*15 gene-allele protein products of HLA-B.[1] B70 is one of many split antigens of the broad antigen, B15.

Serotype

Serotypes B15, B62, B63, B70, B71, B72, B75, B76, B77 recognition of the
HLA B*15 gene products[2]
B*15 B15 B62 B63 B70 B71 B72 B75 B76 B77 Sample
allele % % % % % % % % % size (N)
*1503 1 61 10 2569
*1509 53 65
*1510 1 49 2 2 1 1204
*1518 51 3 552
*1529 19 21
*1537 30 34
Alleles link-out to IMGT/HLA Databease at EBI

Alleles

HLA B*1503 frequencies
freq
ref. Population (%)
[3] Burkina Faso Rimaibe13.8
Guinea Bissau10.8
Cameroon Pygmy Baka10.0
South African Natal Zulu9.5
Kenya Luo8.9
Ivory Coast Akan Adiopodoume8.0
Kenya Nandi7.9
Cameroon Sawa7.7
Zimbabwe Harare Shona7.7
USA African America7.3
Burkina Faso Fulani7.1
Mali Bandiagara6.9
Senegal Niokholo Mandenka6.9
Cape Verde SE Islands6.5
Kenya 6.3
Uganda Kampala6.2
Sudanese6.0
Zambia Lusaka5.7
Cameroon Yaounde4.9
Cape Verde NW Islands4.8
Oman4.7
Cameroon Bamileke4.5
Tunisia Tunis4.5
Cameroon Beti3.7
Brazil Belo Horizonte3.2
Azores Terceira Island2.4
Madeira2.2
Saudi Arabia Guraiat and Hail2.0
Tunisia2.0
United Arab Emerates1.5
Brazil1.4
Cuban White1.4
Morocco Nador Metalsa 1.4
Mexico Mestizos1.2
Italy Bergamo1.1
Portugal North1.1
American Samoa1.0
Iran Baloch1.0
Mexico Guadalajara Mestizos (2)1.0
Azores Central Islands0.9
Israel Ashk. and Non-Ashk. Jews0.9
Taiwan Hakka0.9
Croatia0.7
HLA B*1509 frequencies
freq
ref. Population (%)
[3] Burkina Faso Fulani4.1
India West Coast Parsis3.0
Spain Eastern Andalusia Gipsy3.0
Mexico Mestizos2.4
Italy South Campania1.2
Burkina Faso Rimaibe1.1
China Inner Mongolia1.0
Mali Bandiagara0.7
Czech Republic0.5
HLA B*1510 frequencies
freq
ref. Population (%)
[3] South African Natal Zulu8.5
Zimbabwe Harare Shona8.4
Ivory Coast Akan Adiopodoume5.7
Kenya 5.2
Zambia Lusaka4.6
Cameroon Sawa3.8
Guinea Bissau3.8
Kenya Luo3.6
Senegal Niokholo Mandenka3.2
Cameroon Beti2.8
USA African Americans (3)2.7
Uganda Kampala2.5
Mexico Mestizos2.4
Mali Bandiagara2.2
Kenya Nandi1.7
Brazil Belo Horizonte1.6
Cameroon Bamileke1.3
Cuban Mulatto1.2
Cameroon Yaounde1.1
Iran Baloch1.0
Sudanese1.0
Tunisia1.0
Brazil Terena0.9
Cape Verde NW Islands0.8
United Arab Emerates0.8
USA North American Natives0.8
Guadalajara Mestizos (2)0.5
HLA B*1518 frequencies
freq
ref. Population (%)
[3] South Africa Natal Tamil4.1
Autonomous Tibetans3.8
India Mumbai Marathas3.7
China North Han2.9
USA Hawaii Okinawa2.9
China Guangzhou Han2.4
India Andhra Pradesh Golla2.4
China Beijing2.3
Taiwan Hakka1.8
Japan1.7
India North Delhi1.6
China Inner Mongolia1.5
China Qinghai Hui1.4
Czech Republic1.4
China Yunnan Nu1.3
Shijiazhuang Tianjian Han1.1
Ivory Coast Akan Adiopodoume1.1
Senegal Niokholo Mandenka1.1
Zambia Lusaka1.1
Portugal Centre1.0
Singapore Javanese Indonesians1.0
Thailand (3)1.0
South Korea (3)0.9
Cape Verde Islands0.8
France South East0.8
Guinea Bissau0.8
China South Han0.7
China Yunnan Lisu0.7
Russia Tuva (2)0.6
Singapore Chinese Han0.6
Spain Eastern Andalusia0.6

References

  1. ↑ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. ↑ derived from IMGT/HLA
  3. 1 2 3 4 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)
This article is issued from Wikipedia - version of the Tuesday, September 01, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.