HLA-B*83

major histocompatibility complex (human), class I, B*83
Alleles	B*8301
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B**8301
Locus	chr.6 6p21.31

HLA-B*83 (B83) is an HLA-B allele-group composed of a single allele, B*8301. There is no useful serology associated with this allele.^[1]

It is found in a single Mbenzele Pygmy tribe of the Central Africa Republic at 1.5%.^[2] B*8301 appears to be the result of the replacement of exon 2 from B*4402 with exon 2 from B*5603.^[3] (For terminology help see: HLA-serotype tutorial)

Location of Central African Republic

Location of Africa's Pygmy Tribes

References

1. Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
2. Bruges Armas J, Destro-Bisol G, López-Vazquez A, et al. (2003). "HLA class I variation in the West African Pygmies and their genetic relationship with other African populations". Tissue Antigens 62 (3): 233–42. doi:10.1034/j.1399-0039.2003.00100.x. PMID 12956877.
3. Steiner NK, Gans CP, Kosman C, et al. (2001). "New alleles in the B44 family including B*44022, B*44032, B*4411, B*4420, B*4421, B*4424, and B*8301". Tissue Antigens 57 (4): 376–9. doi:10.1034/j.1399-0039.2001.057004376.x. PMID 11380952.