HLA-B59

major histocompatibility complex (human), class I, B59
Alleles	B*5901
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*5901
Locus	chr.6 6p21.31

HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products.^[1] B59 is a hybrid between B*55 and B*51.^[2] B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)

Serotype

B59 serotype recognition of the HLA B*59 allele-group gene products^[3]

B*59	B59	Other	Sample
allele	%	%	size (N)
5901	45	41	123

B*5901 allele frequencies

HLA B*5901 frequencies

		freq
ref.	Population	(%)
[4]	Okinawan (USA Hawaii)	6.3
[4]	Japan (2)	2.7
[4]	Tarialan Khoton (Mongolia)	2.4
[4]	South Korea (3)	2.1
[4]	Gipuscoa Basque (Spain)	2.0
[4]	Japan Central	1.8
[4]	Casablanca (Morocco)	1.8
[4]	Hyogo (Japan)	1.6
[4]	N. Korean (Harbin,China)	1.0
[4]	Manchu (Harbin, China)	0.6
[4]	Naxi (Yunnan, China)	0.6
[4]	Girona (Catalonia,Spain)	0.6
[4]	Algeria (1)	0.5
[4]	Inner Mongolia (China)	0.5
[4]	Khalkha (Mongolia)	0.5
[4]	Shanghai (China)	0.3
[4]	Essen (German )	0.3
[4]	Southern Han (China)	0.2
[4]	Shij. Tian. (Beijing, China)	0.1
[4]	Hakka (Taiwan)	0.1

Regions of higher B*5901 frequency

Japan
Korea
Mongolia
Heilongjiang prov., China (Harbin city)

References

1. Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
2. Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens 41 (4): 190–5. doi:10.1111/j.1399-0039.1993.tb02001.x. PMID 8362411.
3. derived from IMGT/HLA
4. Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)