HLA-B35

B*3508-β2MG with bound peptide
2h6p
major histocompatibility complex (human), class I, B35
Alleles B*3501, 3502, 3503, . . .
Structure (See HLA-B)
Symbol(s) HLA-B 2fyy, 2fz3
EBI-HLA B*3501 2h6p, 2cik,
1a1n
EBI-HLA B*3502
EBI-HLA B*3503
EBI-HLA B*3504
EBI-HLA B*3505
EBI-HLA B*3506
EBI-HLA B*3507
EBI-HLA B*3508 2nw3, 2nx5
EBI-HLA B*3509
EBI-HLA B*3510
EBI-HLA B*3511
EBI-HLA B*3512
Locus chr.6 6p21.31

HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products.[1] B35 is one of the largest B serotype groups, it currently has 97 known nucleotide variants and 86 polypeptide isoforms. (For terminology help see: HLA-serotype tutorial). This variant is particularly susceptible to HIV infection.

Serotype

B35 serotype recognition of Some HLA B*35 allele-group gene products[2]
B*35 B35 Sample
allele % % size (N)
3501 98 2023
3502 72 1013
3503 94 1226
3504 100 26
3505 94 231
3506 79 10
3508 91 349
3509 68 3
3510 75 12
3511 67 17
3512 78 422
3514 79 29
3520 42 23

References

  1. Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. derived from IMGT/HLA
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