HLA-DO

major histocompatibility complex, class II, DO alpha
Identifiers
Symbol	HLA-DOA
Alt. symbols	HLA-DZA, HLA-DNA
Entrez	3111
HUGO	4936
OMIM	142930
RefSeq	NM_002119
UniProt	Q9TQD3
Other data
Locus	Chr. 6 p21.3

major histocompatibility complex, class II, DO beta
Identifiers
Symbol	HLA-DOB
Entrez	3112
HUGO	4937
OMIM	600629
RefSeq	NM_002120
UniProt	P13765
Other data
Locus	Chr. 6 p21.3

HLA-DO is a dimeric MHC class II protein composed of α- and β-subunits which assists in the down-regulation of HLA-DM.^[1]

References

↑ Fallas JL, Tobin HM, Lou O, Guo D, Sant'Angelo DB, Denzin LK (August 2004). "Ectopic expression of HLA-DO in mouse dendritic cells diminishes MHC class II antigen presentation". J. Immunol. 173 (3): 1549–60. doi:10.4049/jimmunol.173.3.1549. PMID 15265882.

Surface antigens

Major histocompatibility complex/
Human leukocyte antigen

MHC class I	HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G

MHC class II	HLA-DM α β HLA-DO α β HLA-DP α1 β1 HLA-DQ α1 α2 β1 β2 β3 HLA-DR α β1 β3 β4 β5 Minor histocompatibility antigen

Other

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