Lipid-phosphate phosphatase

Lipid-phosphate phosphatase
Identifiers
EC number 3.1.3.76
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, a lipid-phosphate phosphatase (EC 3.1.3.76) is an enzyme that catalyzes the chemical reaction

(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H2O \rightleftharpoons (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate

Thus, the two substrates of this enzyme are (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate and H2O, whereas its two products are (9S,10S)-9,10-dihydroxyoctadecanoate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase. Other names in common use include hydroxy fatty acid phosphatase, dihydroxy fatty acid phosphatase, hydroxy lipid phosphatase, sEH (ambiguous), and soluble epoxide hydrolase (ambiguous).

References

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