Ribonuclease U2

Ribonuclease U2
Identifiers
EC number 3.1.27.4
CAS number 37205-57-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Ribonuclease U2 (EC 3.1.27.4, purine specific endoribonuclease, ribonuclease U3, RNase U3, RNase U2, purine-specific ribonuclease, purine-specific RNase, Pleospora RNase, Trichoderma koningi RNase III, ribonuclease (purine)) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates

References

  1. Glitz, D.G. and Dekker, C.A. (1964). "Studies on a ribonuclease from Ustilago sphaerogena. I. Purification and properties of the enzyme". Biochemistry 3 (10): 1391–1399. doi:10.1021/bi00898a001. PMID 14230791.
  2. Glitz, D.G. and Dekker, C.A. (1964). "Studies on a ribonuclease from Ustilago sphaerogena. II. Specificity of the enzyme". Biochemistry 3 (10): 1399–1406. doi:10.1021/bi00898a002. PMID 14230792.
  3. Uchida, T. and Egami, F. Microbial ribonucleases with special reference to RNases T1, T 2, N (1971). "1, and U2". In Boyer, P.D. The Enzymes 4 (3rd ed.). New York: Academic Press. pp. 205–250.

External links

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