Sodium ferulate

Sodium ferulate

Names
IUPAC name Sodium (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
Identifiers
CAS Number	24276-84-4
ChEBI	CHEBI:114954
ChemSpider	4479130
Jmol 3D model	Interactive image
PubChem	5321361
InChI InChI=1S/C10H10O4.Na/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13;/h2-6,11H,1H3,(H,12,13);/q;+1/p-1/b5-3+; Key: NCTHNHPAQAVBEB-WGCWOXMQSA-M InChI=1/C10H10O4.Na/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13;/h2-6,11H,1H3,(H,12,13);/q;+1/p-1/b5-3+; Key: NCTHNHPAQAVBEB-OLHRVHTCBT
SMILES [Na+].[O-]C(=O)\C=C\c1cc(OC)c(O)cc1
Properties
Chemical formula	C10H9NaO4
Molar mass	216.17 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Sodium ferulate (SF), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis. It is found in the root of Angelica sinensis. It is considered safe and effective.^[1] Ferulic acid can also be extracted from the root of the Chinese herb Ligusticum chuanxiong.^[2]

Kraft Foods patented the use of sodium ferulate to mask the aftertaste of the artificial sweetener acesulfame potassium.^[3]

References

1. Wang, B. H.; Ou-Yang, J. P. (2005). "Pharmacological Actions of Sodium Ferulate in Cardiovascular System". Cardiovascular Drug Reviews 23 (2): 161–172. doi:10.1111/j.1527-3466.2005.tb00163.x. PMID 16007232.
2. Wang, W.; Sun, Y. (2008). "Ultrasonic Extraction of Ferulic Acid from Ligusticum chuanxiong". Journal of the Chinese Institute of Chemical Engineers 39 (6): 653–656. doi:10.1016/j.jcice.2008.05.012.
3. US patent 5336513, Riemer, J. A., "Bitterness Inhibitors", issued 1994-08-09, assigned to Kraft General Foods  (expired in 2006 due to non-payment of fees)