Bamifylline
Bamifylline
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Names |
IUPAC name
8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione |
Identifiers |
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2016-63-9 N |
ChEMBL |
ChEMBL2110760 N |
ChemSpider |
15401 Y |
Jmol interactive 3D |
Image |
PubChem |
16229 |
UNII |
ZTY15D026H Y |
InChI=1S/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3 YKey: VVUYEFBRTFASAH-UHFFFAOYSA-N YInChI=1/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3 Key: VVUYEFBRTFASAH-UHFFFAOYAJ
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O=C2N(c1nc(n(c1C(=O)N2C)CCN(CC)CCO)Cc3ccccc3)C
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Properties |
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C20H27N5O3 |
Molar mass |
385.46008 |
Pharmacology |
ATC code |
R03DA08 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
N verify (what is YN ?) |
Infobox references |
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Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.[1][2]
See also
References
- ↑ Tomai F, Crea F, Gaspardone A, Versaci F, De Paulis R, Polisca P, Chiariello L, Gioffrè PA (June 1996). "Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty". European Heart Journal 17 (6): 846–53. doi:10.1093/oxfordjournals.eurheartj.a014965. PMID 8781823.
- ↑ Kofman, J.; Grosclaude, M.; Ouechni, M. M.; Perrin-Fayolle, M. (1982). "Comparative effects of bamifylline and theophylline on allergenic bronchospasm induced by the provocative inhalation test : Double-blind cross-over study". Le Poumon et le coeur 38 (3): 197–202. PMID 6752929.