Equilibrative nucleoside transporter
The equilibrative nucleoside transporter (ENT) family, also known as SLC29, is a group of plasmalemmal transport proteins which transport nucleoside substrates like adenosine into cells.[1] There are four known ENTs, designated ENT1, ENT2, ENT3, and ENT4.[1][2] ENTs are blocked by adenosine reuptake inhibitors like dipyridamole and dilazep, drugs used clinically for their vasodilatory properties.[2][3]
See also
References
- 1 2 Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (Feb 2004). "The equilibrative nucleoside transporter family, SLC29". Pflügers Archiv 447 (5): 735–43. doi:10.1007/s00424-003-1103-2. PMID 12838422.
- 1 2 Molina-Arcas M, Casado FJ, Pastor-Anglada M (Oct 2009). "Nucleoside transporter proteins". Current Vascular Pharmacology 7 (4): 426–34. PMID 19485885.
- ↑ Noji T, Karasawa A, Kusaka H (Jul 2004). "Adenosine uptake inhibitors". European Journal of Pharmacology 495 (1): 1–16. doi:10.1016/j.ejphar.2004.05.003. PMID 15219815.
Further reading
- Molina-Arcas M, Casado FJ, Pastor-Anglada M (Oct 2009). "Nucleoside transporter proteins". Current Vascular Pharmacology 7 (4): 426–34. PMID 19485885.
- Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (Feb 2004). "The equilibrative nucleoside transporter family, SLC29". Pflügers Archiv 447 (5): 735–43. doi:10.1007/s00424-003-1103-2. PMID 12838422.
- Molina-Arcas M, Trigueros-Motos L, Casado FJ, Pastor-Anglada M (Jun 2008). "Physiological and pharmacological roles of nucleoside transporter proteins". Nucleosides, Nucleotides & Nucleic Acids 27 (6): 769–78. doi:10.1080/15257770802145819. PMID 18600539.
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| SLC1–10 |
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| | SLC11–20 |
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| (11): |
- proton coupled metal ion transporter
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| (12): | |
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| (13): |
- human Na+-sulfate/carboxylate cotransporter
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| (14): | |
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| (15): |
- proton oligopeptide cotransporter
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| (16): |
- monocarboxylate transporter
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| (18): | |
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| (20): | |
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| | SLC21–30 |
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| (21): | |
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| (22): | |
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| (23): |
- Na+-dependent ascorbic acid transporter
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| (25): | |
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| (26): |
- multifunctional anion exchanger
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| (27): | |
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| (28): |
- Na+-coupled nucleoside transport (SLC28A1
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| (29): |
- facilitative nucleoside transporter
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| (30): | |
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| | SLC31–40 |
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| (33): | |
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| (34): |
- type II Na+-phosphate cotransporter
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| (35): |
- nucleoside-sugar transporter
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- SLC35E1
- SLC35E2
- SLC35E3
- SLC35E4
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| (36): |
- proton-coupled amino-acid transporter
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| (37): |
- sugar-phosphate/phosphate exchanger
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| (38): |
- System A & N, sodium-coupled neutral amino-acid transporter
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| (39): | |
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| (40): |
- basolateral iron transporter
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| | SLC41–48 |
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| (41): | |
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| (42): | |
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| (43): |
- Na+-independent, system-L like amino-acid transporter
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| (44): | |
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| (45): |
- Putative sugar transporter
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| (48): | |
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| | | | see also solute carrier disorders |
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