SLC2A6

Solute carrier family 2 (facilitated glucose transporter), member 6
Identifiers
Symbols	SLC2A6 ; GLUT6; GLUT9; HSA011372
External IDs	OMIM: 606813 MGI: 2443286 HomoloGene: 69236 GeneCards: SLC2A6 Gene
Gene ontology Molecular function • sugar:proton symporter activity • glucose transmembrane transporter activity Cellular component • plasma membrane • integral component of plasma membrane • membrane Biological process • proton transport • hexose transmembrane transport • glucose import • transmembrane transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11182	227659
Ensembl	ENSG00000160326	ENSMUSG00000036067
UniProt	Q9UGQ3	A2AR26
RefSeq (mRNA)	NM_001145099	NM_001177627
RefSeq (protein)	NP_001138571	NP_001171098
Location (UCSC)	Chr 9: 133.47 – 133.48 Mb	Chr 2: 27.02 – 27.03 Mb
PubMed search

Solute carrier family 2, facilitated glucose transporter member 6 is a protein that in humans is encoded by the SLC2A6 gene.^[1][2]

Hexose transport into mammalian cells is catalyzed by a family of membrane proteins, including SLC2A6, that contain 12 transmembrane domains and a number of critical conserved residues.[supplied by OMIM]^[2]

See also

• Glucose transporter
• Solute carrier family

References

1. Doege H, Bocianski A, Joost HG, Schurmann A (Jan 2001). "Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes". Biochem J. 350 Pt 3 (Pt 3): 771–6. doi:10.1042/0264-6021:3500771. PMC 1221309. PMID 10970791.
2. "Entrez Gene: SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Richardson S, Neama G, Phillips T, et al. (2003). "Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation". Osteoarthr. Cartil. 11 (2): 92–101. doi:10.1053/joca.2002.0858. PMID 12554125.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.