SLC2A12

Solute carrier family 2 (facilitated glucose transporter), member 12
Identifiers
Symbols	SLC2A12 ; GLUT12; GLUT8
External IDs	OMIM: 610372 MGI: 3052471 HomoloGene: 59263 GeneCards: SLC2A12 Gene
Gene ontology Molecular function • sugar:proton symporter activity • glucose transmembrane transporter activity Cellular component • plasma membrane • integral component of plasma membrane • endomembrane system • perinuclear region of cytoplasm Biological process • proton transport • hexose transmembrane transport • glucose import • transmembrane transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	154091	353169
Ensembl	ENSG00000146411	ENSMUSG00000037490
UniProt	Q8TD20	Q8BFW9
RefSeq (mRNA)	NM_145176	NM_178934
RefSeq (protein)	NP_660159	NP_849265
Location (UCSC)	Chr 6: 133.99 – 134.05 Mb	Chr 10: 22.65 – 22.7 Mb
PubMed search

Solute carrier family 2, facilitated glucose transporter member 12 is a protein that in humans is encoded by the SLC2A12 gene.^[1][2][3]

See also

• Glucose transporter
• Solute carrier family

References

1. Joost HG, Thorens B (Jan 2002). "The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)". Mol Membr Biol 18 (4): 247–56. doi:10.1080/09687680110090456. PMID 11780753.
2. Rogers S, Macheda ML, Docherty SE, Carty MD, Henderson MA, Soeller WC, Gibbs EM, James DE, Best JD (Feb 2002). "Identification of a novel glucose transporter-like protein-GLUT-12". Am J Physiol Endocrinol Metab 282 (3): E733–8. PMID 11832379.
3. "Entrez Gene: SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12".

Further reading

• Baumann MU, Deborde S, Illsley NP (2003). "Placental glucose transfer and fetal growth.". Endocrine 19 (1): 13–22. doi:10.1385/ENDO:19:1:13. PMID 12583599.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wood IS, Hunter L, Trayhurn P (2003). "Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues.". Biochem. Biophys. Res. Commun. 308 (1): 43–9. doi:10.1016/S0006-291X(03)01322-6. PMID 12890477.
• Rogers S, Chandler JD, Clarke AL, et al. (2003). "Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes.". Biochem. Biophys. Res. Commun. 308 (3): 422–6. doi:10.1016/S0006-291X(03)01417-7. PMID 12914765.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Linden KC, DeHaan CL, Zhang Y, et al. (2006). "Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy.". Am. J. Physiol. Renal Physiol. 290 (1): F205–13. doi:10.1152/ajprenal.00237.2004. PMID 16091581.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Stuart CA, Yin D, Howell ME, et al. (2006). "Hexose transporter mRNAs for GLUT4, GLUT5, and GLUT12 predominate in human muscle.". Am. J. Physiol. Endocrinol. Metab. 291 (5): E1067–73. doi:10.1152/ajpendo.00250.2006. PMID 16803853.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.