SLC27A1
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Long-chain fatty acid transport protein 1 is a protein that in humans is encoded by the SLC27A1 gene.[1][2]
Structure
The SLC27A1 gene is located on the 19th chromosome, with its specific location being 19p13.11. The gene contains 15 exons.[2] SLC27A1 encodes a 71.1 kDa protein that is composed of 646 amino acids; 26 peptides have been observed through mass spectrometry data.[3][4]
See also
- SLC27A1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- Solute carrier family
References
- ↑ Martin G, Nemoto M, Gelman L, Geffroy S, Najib J, Fruchart JC, Roevens P, de Martinville B, Deeb S, Auwerx J (Sep 2000). "The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression". Genomics 66 (3): 296–304. doi:10.1006/geno.2000.6191. PMID 10873384.
- 1 2 "Entrez Gene: SLC27A1 solute carrier family 27 (fatty acid transporter), member 1".
- ↑ ]Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N, Kim AK, Choi JH, Zelaya I, Liem D, Meyer D, Odeberg J, Fang C, Lu HJ, Xu T, Weiss J, Duan H, Uhlen M, Yates JR, Apweiler R, Ge J, Hermjakob H, Ping P (Oct 2013). "Integration of cardiac proteome biology and medicine by a specialized knowledgebase". Circulation Research 113 (9): 1043–53. doi:10.1161/CIRCRESAHA.113.301151. PMC 4076475. PMID 23965338.
- ↑ "Long-chain fatty acid transport protein 1". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB).
Further reading
- Meirhaeghe A, Cottel D, Amouyel P, Dallongeville J (2006). "Lack of association between certain candidate gene polymorphisms and the metabolic syndrome.". Mol. Genet. Metab. 86 (1–2): 293–9. doi:10.1016/j.ymgme.2005.05.006. PMID 15978856.
- García-Martínez C, Marotta M, Moore-Carrasco R, et al. (2005). "Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells". Am. J. Physiol., Cell Physiol. 288 (6): C1264–72. doi:10.1152/ajpcell.00271.2004. PMID 15897321.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Gertow K, Skoglund-Andersson C, Eriksson P, et al. (2003). "A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution". Atherosclerosis 167 (2): 265–73. doi:10.1016/S0021-9150(02)00454-9. PMID 12818409.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Hatch GM, Smith AJ, Xu FY, et al. (2003). "FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells". J. Lipid Res. 43 (9): 1380–9. doi:10.1194/jlr.M200130-JLR200. PMID 12235169.
- Hirsch D, Stahl A, Lodish HF (1998). "A family of fatty acid transporters conserved from mycobacterium to man". Proc. Natl. Acad. Sci. U.S.A. 95 (15): 8625–9. doi:10.1073/pnas.95.15.8625. PMC 21126. PMID 9671728.
- Schaffer JE, Lodish HF (1994). "Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein". Cell 79 (3): 427–36. doi:10.1016/0092-8674(94)90252-6. PMID 7954810.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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