Tetramethylpyrazine

Tetramethylpyrazine
Names
IUPAC name
2,3,5,6-Tetramethylpyrazine
Other names
Ligustrazine; Tetrapyrazine
Identifiers
1124-11-4
Jmol interactive 3D Image
PubChem 14296
Properties
C8H12N2
Molar mass 136.20 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tetramethylpyrazine, also known as ligustrazine, is an antiinflammatory compound isolated from the fermented food natto.[1][1] It demonstrated in vivo nootropic activity in rats.[2]

References

  1. 1 2 Kao, TK; Chang, CY; Ou, YC; Chen, WY; Kuan, YH; Pan, HC; Liao, SL; Li, GZ; Chen, CJ (2013). "Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats". Experimental neurology 247: 188–201. doi:10.1016/j.expneurol.2013.04.010. PMID 23644042.
  2. Wu, W; Yu, X; Luo, XP; Yang, SH; Zheng, D (2013). "Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway". Behavioural Brain Research 253: 212–6. doi:10.1016/j.bbr.2013.07.052. PMID 23916742.


This article is issued from Wikipedia - version of the Sunday, January 31, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.