6-phospho-beta-galactosidase

6-phospho-beta-galactosidase
Identifiers
EC number	3.2.1.85
CAS number	37237-42-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

In enzymology, a 6-phospho-beta-galactosidase (EC 3.2.1.85) is an enzyme that catalyzes the chemical reaction

a 6-phospho-beta-D-galactoside + H₂O $\rightleftharpoons$ 6-phospho-D-galactose + an alcohol

Thus, the two substrates of this enzyme are 6-phospho-beta-D-galactoside and H₂O, whereas its two products are 6-phospho-D-galactose and alcohol.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 6-phospho-beta-D-galactoside 6-phosphogalactohydrolase. Other names in common use include phospho-beta-galactosidase, beta-D-phosphogalactoside galactohydrolase, phospho-beta-D-galactosidase, and 6-phospho-beta-D-galactosidase. This enzyme participates in galactose metabolism.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1PBG, 2PBG, 3PBG, and 4PBG.

References

• Hengstenberg W, Penberthy WK, Morse ML (1970). "Purification of the staphylococcal 6-phospho-beta-D-- galactosidase". Eur. J. Biochem. 14 (1): 27–32. doi:10.1111/j.1432-1033.1970.tb00256.x. PMID 5447434.