Oxypurinol

Oxypurinol
Names
Preferred IUPAC name
1,2-Dihydropyrazolo[4,3-e]pyrimidine-4,6-dione
Systematic IUPAC name
1H,2H,4H,5H,6H-pyrazolo[3,4-d]pyrimidine-4,6-dione
Other names
1H,2H,5H-pyrazolo[3,4-d]pyrimidine-4,6-dione
Alloxanthine
Identifiers
2465-59-0
139956
ChEBI CHEBI:28315
ChEMBL ChEMBL859 YesY
ChemSpider 4483
EC Number 219-570-9
Jmol interactive 3D Image
KEGG C07599
MeSH Oxypurinol
PubChem 4644
UNII G97OZE5068
Properties
C5H4N4O2
Molar mass 152.11086
Appearance white crystals
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Oxypurinol is an inhibitor of xanthine oxidase. It is an active metabolite of allopurinol and it is cleared renally. In cases of renal disease, this metabolite will accumulate to toxic levels. By inhibiting xanthine oxidase, it reduces uric acid production. High serum uric acid levels may result in gout, kidney stones, and other medical conditions.

References



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