Blood-group-substance endo-1,4-beta-galactosidase

Identifiers

Databases

IntEnz

IntEnz view

PDB structures

Search
PMC	articles
PubMed	articles
NCBI	proteins

Blood-group-substance endo-1,4-beta-galactosidase (EC 3.2.1.102, endo-beta-galactosidase, blood-group-substance 1,4-beta-D-galactanohydrolase) is an enzyme with systematic name blood-group-substance 4-beta-D-galactanohydrolase.^[1]^[2]^[3] This enzyme catalyses the following chemical reaction

Endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances

Hydrolyses the 1,4-beta-D-galactosyl linkages adjacent to a 1,3-alpha-D-galactosyl or N-acetylgalactosaminyl residues and a 1,2-alpha-D-fucosyl residue.

References

↑ Fukuda, M.N. and Matsumara, G. (1976). "Endo-β-galactosidase of Escherichia freundii. Purification and endoglycosidic action on keratan sulfates, oligosaccharides, and blood group active glycoprotein". J. Biol. Chem. 251: 6218–6225. PMID 135762.
↑ Nakazawa, K. and Suzuki, S. (1975). "Purification of keratan sulfate-endogalactosidase and its action on keratan sulfates of different origin". J. Biol. Chem. 250: 912–917. PMID 234443.
↑ Takasaki, S. and Kobata, A. (1976). "Purification and characterization of an endo-β-galactosidase produced by Diplococcus pneumoniae". J. Biol. Chem. 251: 3603–3609. PMID 6459.

External links

Blood-group-substance endo-1,4-beta-galactosidase at the US National Library of Medicine Medical Subject Headings (MeSH)

Hydrolase: sugar hydrolases (EC 3.2)

3.2.1: Glycoside hydrolases

Disaccharidase	Sucrase/Sucrase-isomaltase/Invertase Maltase Trehalase Lactase

Glucosidases	Cellulase Alpha-glucosidase Acid Neutral AB Neutral C Beta-glucosidase cytosolic Debranching enzyme

Other	Amylase Alpha-amylase Chitinase Lysozyme Neuraminidase NEU1 NEU2 NEU3 NEU4 Bacterial neuraminidase Viral neuraminidase Galactosidases Alpha Beta alpha-Mannosidase Glucuronidase Hyaluronidase Pullulanase Glucosylceramidase lysosomal non-lysosomal Galactosylceramidase Alpha-N-acetylgalactosaminidase NAGA Alpha-N-acetylglucosaminidase Fucosidase Hexosaminidase HEXA HEXB Iduronidase Maltase-glucoamylase Heparanase HPSE2

3.2.2: Hydrolysing
N-Glycosyl compounds

DNA glycosylases: Oxoguanine glycosylase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

This article is issued from Wikipedia - version of the Thursday, March 31, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.