Blood group B linear chain alpha-1,3-galactosidase

Baicalin-beta-D-glucuronidase
Identifiers
EC number	3.2.1.167
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Baicalin-beta-D-glucuronidase (EC 3.2.1.167, baicalinase) is an enzyme with systematic name 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase.^[1][2][3][4] This enzyme catalyses the following chemical reaction

baicalin + H₂O $\rightleftharpoons$ baicalein + D-glucuronate

The enzyme also hydrolyses wogonin 7-O-beta-D-glucuronide and oroxylin 7-O-beta-D-glucuronide with lower efficiency.

References

1. Ikegami, F., Matsunae, K., Hisamitsu, M., Kurihara, T., Yamamoto, T. and Murakoshi, I. (1995). "Purification and properties of a plant β-D-glucuronidase form Scutellaria root". Biol. Pharm. Bull. 18: 1531–1534. doi:10.1248/bpb.18.1531. PMID 8593473.
2. Zhang, C., Zhang, Y., Chen, J. and Liang, X. (2005). "Purification and characterization of baicalin-β-D-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of Scutellaria viscidula Bge". Proc. Biochem. 40: 1911–1915. doi:10.1016/j.procbio.2004.07.003.
3. Sasaki, K., Taura, F., Shoyama, Y. and Morimoto, S. (2000). "Molecular characterization of a novel β-glucuronidase from Scutellaria baicalensis Georgi". J. Biol. Chem. 275: 27466–27472. doi:10.1074/jbc.m004674200. PMID 10858442.
4. Morimoto, S., Harioka, T. and Shoyama, Y. (1995). "Purification and characterization of flavone-specific β-glucuronidase from callus cultures of Scutellaria baicalensis Georgi". Planta 195: 535–540. doi:10.1007/bf00195712.

External links

• Baicalin-beta-D-glucuronidase at the US National Library of Medicine Medical Subject Headings (MeSH)