CENPM

Centromere protein M
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 4P0T​, 4WAU​
Identifiers
Symbols	CENPM ; C22orf18; CENP-M; PANE1
External IDs	OMIM: 610152 MGI: 1913820 HomoloGene: 11438 GeneCards: CENPM Gene
Gene ontology Cellular component • condensed chromosome kinetochore • nucleoplasm • cytosol Biological process • mitotic cell cycle • nucleosome assembly • small GTPase mediated signal transduction • CENP-A containing nucleosome assembly Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	79019	66570
Ensembl	ENSG00000100162	ENSMUSG00000068101
UniProt	Q9NSP4	Q9CQA0
RefSeq (mRNA)	NM_001002876	NM_001080158
RefSeq (protein)	NP_001002876	NP_001073627
Location (UCSC)	Chr 22: 41.94 – 41.95 Mb	Chr 15: 82.23 – 82.24 Mb
PubMed search

Centromere protein M is a protein that in humans is encoded by the CENPM gene.^[1][2][3]

References

1. Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T (May 2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nat Cell Biol 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420.
2. Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR 3rd, Cleveland DW (May 2006). "The human CENP-A centromeric nucleosome-associated complex". Nat Cell Biol 8 (5): 458–69. doi:10.1038/ncb1397. PMID 16622419.
3. "Entrez Gene: CENPM centromere protein M".

Further reading

• Dunham I, Shimizu N, Roe BA; et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Collins JE, Goward ME, Cole CG; et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22.". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Obuse C, Yang H, Nozaki N; et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.". Genes Cells 9 (2): 105–20. doi:10.1111/j.1365-2443.2004.00705.x. PMID 15009096.
• Bierie B, Edwin M, Melenhorst JJ, Hennighausen L (2005). "The proliferation associated nuclear element (PANE1) is conserved between mammals and fish and preferentially expressed in activated lymphoid cells.". Gene Expr. Patterns 4 (4): 389–95. doi:10.1016/j.modgep.2004.01.008. PMID 15183305.
• Collins JE, Wright CL, Edwards CA; et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Brickner AG, Evans AM, Mito JK; et al. (2006). "The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL.". Blood 107 (9): 3779–86. doi:10.1182/blood-2005-08-3501. PMC 1895781. PMID 16391015.
• Izuta H, Ikeno M, Suzuki N; et al. (2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.". Genes Cells 11 (6): 673–84. doi:10.1111/j.1365-2443.2006.00969.x. PMID 16716197.