CENPO

Centromere protein O
Identifiers
Symbols	CENPO ; CENP-O; ICEN-36; MCM21R
External IDs	OMIM: 611504 MGI: 1923800 HomoloGene: 49760 GeneCards: CENPO Gene
Gene ontology Molecular function • protein binding Cellular component • condensed chromosome kinetochore • nucleoplasm • cytosol Biological process • mitotic cell cycle • nucleosome assembly • small GTPase mediated signal transduction • CENP-A containing nucleosome assembly Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	79172	52504
Ensembl	ENSG00000138092	ENSMUSG00000020652
UniProt	Q9BU64	Q8K015
RefSeq (mRNA)	NM_001199803	NM_134046
RefSeq (protein)	NP_001186732	NP_598807
Location (UCSC)	Chr 2: 24.79 – 24.82 Mb	Chr 12: 4.2 – 4.23 Mb
PubMed search

Centromere protein O is a protein that in humans is encoded by the CENPO gene.^[1][2][3]

References

1. Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T (May 2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nat Cell Biol 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420.
2. Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR 3rd, Cleveland DW (May 2006). "The human CENP-A centromeric nucleosome-associated complex". Nat Cell Biol 8 (5): 458–69. doi:10.1038/ncb1397. PMID 16622419.
3. "Entrez Gene: CENPO centromere protein O".

Further reading

• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Obuse C, Yang H, Nozaki N; et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.". Genes Cells 9 (2): 105–20. doi:10.1111/j.1365-2443.2004.00705.x. PMID 15009096.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Hillier LW, Graves TA, Fulton RS; et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Izuta H, Ikeno M, Suzuki N; et al. (2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.". Genes Cells 11 (6): 673–84. doi:10.1111/j.1365-2443.2006.00969.x. PMID 16716197.