CENPT

Centromere protein T
Identifiers
Symbols	CENPT ; C16orf56; CENP-T
External IDs	OMIM: 611510 MGI: 2443939 HomoloGene: 41610 GeneCards: CENPT Gene
Gene ontology Molecular function • DNA binding • protein binding • protein heterodimerization activity Cellular component • chromosome, centromeric region • kinetochore • condensed chromosome kinetochore • nucleus • nucleoplasm • cytosol Biological process • mitotic cell cycle • nucleosome assembly • chromosome segregation • mitotic nuclear division • small GTPase mediated signal transduction • CENP-A containing nucleosome assembly • chromosome organization • cell division • kinetochore assembly Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	80152	320394
Ensembl	ENSG00000102901	ENSMUSG00000036672
UniProt	Q96BT3	Q3TJM4
RefSeq (mRNA)	NM_025082	NM_177150
RefSeq (protein)	NP_079358	NP_796124
Location (UCSC)	Chr 16: 67.83 – 67.85 Mb	Chr 8: 105.84 – 105.85 Mb
PubMed search

Centromere protein T is a protein that in humans is encoded by the CENPT gene.^[1][2][3]

References

1. Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T (May 2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nat Cell Biol 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420.
2. Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR 3rd, Cleveland DW (May 2006). "The human CENP-A centromeric nucleosome-associated complex". Nat Cell Biol 8 (5): 458–69. doi:10.1038/ncb1397. PMID 16622419.
3. "Entrez Gene: CENPT centromere protein T".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Obuse C, Yang H, Nozaki N, et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase". Genes Cells 9 (2): 105–20. doi:10.1111/j.1365-2443.2004.00705.x. PMID 15009096.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Izuta H, Ikeno M, Suzuki N, et al. (2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells". Genes Cells 11 (6): 673–84. doi:10.1111/j.1365-2443.2006.00969.x. PMID 16716197.