CYP27C1

Cytochrome P450, family 27, subfamily C, polypeptide 1
Identifiers
Symbols	CYP27C1 ; FLJ16008
External IDs	HomoloGene: 70240 IUPHAR: 1371 GeneCards: CYP27C1 Gene
EC number	1.14.-.-
Gene ontology Molecular function • monooxygenase activity • iron ion binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • heme binding Cellular component • membrane Biological process • oxidation-reduction process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	339761	n/a
Ensembl	ENSG00000186684	n/a
UniProt	Q4G0S4	n/a
RefSeq (mRNA)	NM_001001665	n/a
RefSeq (protein)	NP_001001665	n/a
Location (UCSC)	Chr 2: 127.18 – 127.22 Mb	n/a
PubMed search		n/a

CYP27C1 (cytochrome P450, family 27, subfamily C, polypeptide 1) is a protein that in humans is encoded by the CYP27C1 gene.^[1][2]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.^[3]

References

1. Ota T, Suzuki Y, Nishikawa T; et al. (January 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
2. Gerhard DS, Wagner L, Feingold EA; et al. (October 2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
3. "Entrez Gene: CYP39A1".

Further reading

• Strausberg RL, Feingold EA, Grouse LH; et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Nelson DR, Zeldin DC, Hoffman SM; et al. (2004). "Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.". Pharmacogenetics 14 (1): 1–18. doi:10.1097/00008571-200401000-00001. PMID 15128046.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.