Chitosanase

Chitosanase
Identifiers
EC number	3.2.1.132
CAS number	51570-20-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Chitosanase (EC 3.2.1.132) is an enzyme with systematic name chitosan N-acetylglucosaminohydrolase.^[1][2][3][4] This enzyme catalyses the following chemical reaction

Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan

A whole spectrum of chitosanases are known.

References

1. Fenton, D.M. and Eveleigh, D.E. (1981). "Purification and mode of action of a chitosanase from Penicillium islandicum". J. Gen. Microbiol. 126: 151–165. doi:10.1099/00221287-126-1-151.
2. Saito, J.-I., Kita, A., Higuchi, Y., Nagata, Y., Ando, A. and Miki, K. (1999). "Crystal structure of chitosanase from Bacillus circulans MH-K1 at 1.6-Å resolution and its substrate recognition mechanism". J. Biol. Chem. 274: 30818–30825. doi:10.1074/jbc.274.43.30818. PMID 10521473.
3. Izume, M., Nagae, S., Kawagishi, H., Mitsutomi, M. and Ohtakara, A. (1992). "Action pattern of Bacillus sp. No. 7-M chitosanase on partially N-acetylated chitosan". Biosci. Biotechnol. Biochem. 56: 448–453. doi:10.1271/bbb.56.448. PMID 1368330.
4. Marcotte, E.M., Monzingo, A.F., Ernst, S.R., Brzezinski, R. and Robertus, J.D. (1996). "X-ray structure of an anti-fungal chitosanase from Streptomyces N174". Nat. Struct. Biol. 3: 155–162. doi:10.1038/nsb0296-155. PMID 8564542.

External links

• Chitosanase at the US National Library of Medicine Medical Subject Headings (MeSH)