Cyclomaltodextrinase

cyclomaltodextrinase
Identifiers
EC number	3.2.1.54
CAS number	37288-41-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a cyclomaltodextrinase (EC 3.2.1.54) is an enzyme that catalyzes the chemical reaction

cyclomaltodextrin + H₂O $\rightleftharpoons$ linear maltodextrin

Thus, the two substrates of this enzyme are cyclomaltodextrin and H₂O, whereas its product is linear maltodextrin.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is cyclomaltodextrin dextrin-hydrolase (decyclizing). Other names in common use include cycloheptaglucanase, cyclohexaglucanase, and cyclodextrinase. This enzyme participates in starch and sucrose metabolism.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1EA9 and 1H3G.

References

• DePinto JA, Campbell LL (1968). "Purification and properties of the cyclodextrinase of Bacillus macerans". Biochemistry. 7 (1): 121–5. doi:10.1021/bi00841a016. PMID 4922856.