Glucuronosyl-disulfoglucosamine glucuronidase

glucuronosyl-disulfoglucosamine glucuronidase
Identifiers
EC number	3.2.1.56
CAS number	37288-42-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a glucuronosyl-disulfoglucosamine glucuronidase (EC 3.2.1.56) is an enzyme that catalyzes the following chemical reaction:

3-D-glucuronosyl-N₂,6-disulfo-beta-D-glucosamine + H₂O $\rightleftharpoons$ D-glucuronate + N₂,6-disulfo-D-glucosamine

Thus, the two substrates of this enzyme are 3-D-glucuronosyl-N2,6-disulfo-beta-D-glucosamine and H₂O, whereas its two products are D-glucuronate and N2,6-disulfo-D-glucosamine.

This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 3-D-glucuronsyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase. Other names in common use include glycuronidase, and 3-D-glucuronsyl-2-N,6-disulfo-beta-D-glucosamine glucuronohydrolase.

References

• Dietrich CP (1969). "Enzymic degradation of heparin. A glucosaminidase and a glycuronidase from Flavobacterium heparinum". Biochemistry. 8 (5): 2089–94. doi:10.1021/bi00833a046. PMID 5785227.