Iota-carrageenase

Iota-carrageenase
Identifiers
EC number	3.2.1.157
CAS number	50936-37-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Iota-carrageenase (EC 3.2.1.157) is an enzyme with systematic name iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting).^[1][2][3] This enzyme catalyses the following chemical reaction

Endohydrolysis of (1->4)-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans

The main products of hydrolysis are iota-neocarratetraose sulfate and iota-neocarrahexaose sulfate.

References

1. Barbeyron, T., Michel, G., Potin, P., Henrissat, B. and Kloareg, B. (2000). "ι-Carrageenases constitute a novel family of glycoside hydrolases, unrelated to that of κ-carrageenases". J. Biol. Chem. 275 (45): 35499–35505. doi:10.1074/jbc.m003404200. PMID 10934194.
2. Michel, G., Chantalat, L., Fanchon, E., Henrissat, B., Kloareg, B. and Dideberg, O. (2001). "The ι-carrageenase of Alteromonas fortis. A β-helix fold-containing enzyme for the degradation of a highly polyanionic polysaccharide". J. Biol. Chem. 276 (43): 40202–40209. doi:10.1074/jbc.M100670200. PMID 11493601.
3. Michel, G., Helbert, W., Kahn, R., Dideberg, O. and Kloareg, B. (2003). "The structural bases of the processive degradation of ι-carrageenan, a main cell wall polysaccharide of red algae". J. Mol. Biol. 334 (3): 421–433. doi:10.1016/j.jmb.2003.09.056. PMID 14623184.

External links

• Iota-carrageenase at the US National Library of Medicine Medical Subject Headings (MeSH)