Mucin 7

For the MUC-7 conference, see Message Understanding Conference.

Mucin 7, secreted
Identifiers
Symbols	MUC7 ; MG2
External IDs	OMIM: 158375 HomoloGene: 133350 GeneCards: MUC7 Gene
Gene ontology Molecular function • protein binding Cellular component • Golgi lumen • extracellular exosome Biological process • protein O-linked glycosylation • O-glycan processing • post-translational protein modification • cellular protein metabolic process Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4589	n/a
Ensembl	ENSG00000171195	n/a
UniProt	Q8TAX7	n/a
RefSeq (mRNA)	NM_001145006	n/a
RefSeq (protein)	NP_001138478	n/a
Location (UCSC)	Chr 4: 70.43 – 70.48 Mb	n/a
PubMed search		n/a

Mucin-7 is a protein that in humans is encoded by the MUC7 gene.^[1][2]

References

1. Bobek LA, Liu J, Sait SN, Shows TB, Bobek YA, Levine MJ (Mar 1997). "Structure and chromosomal localization of the human salivary mucin gene, MUC7". Genomics 31 (3): 277–82. doi:10.1006/geno.1996.0049. PMID 8838308.
2. "Entrez Gene: MUC7 mucin 7, secreted".

Further reading

• Zalewska A, Zwierz K, Zółkowski K, Gindzieński A (2002). "Structure and biosynthesis of human salivary mucins.". Acta Biochim. Pol. 47 (4): 1067–79. PMID 11996097.
• Bobek LA, Tsai H, Biesbrock AR, Levine MJ (1993). "Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7).". J. Biol. Chem. 268 (27): 20563–9. PMID 7690757.
• Troxler RF, Iontcheva I, Oppenheim FG, et al. (1998). "Molecular characterization of a major high molecular weight mucin from human sublingual gland.". Glycobiology 7 (7): 965–73. doi:10.1093/glycob/7.7.965. PMID 9363439.
• Prakobphol A, Thomsson KA, Hansson GC, et al. (1998). "Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity.". Biochemistry 37 (14): 4916–27. doi:10.1021/bi972612a. PMID 9538010.
• Kirkbride HJ, Bolscher JG, Nazmi K, et al. (2001). "Genetic polymorphism of MUC7: allele frequencies and association with asthma.". Eur. J. Hum. Genet. 9 (5): 347–54. doi:10.1038/sj.ejhg.5200642. PMID 11378823.
• Guo JM, Zhang Y, Cheng L, et al. (2002). "Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12.". FEBS Lett. 524 (1–3): 211–8. doi:10.1016/S0014-5793(02)03007-7. PMID 12135769.
• Cheng L, Tachibana K, Zhang Y, et al. (2002). "Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10". FEBS Lett. 531 (2): 115–21. doi:10.1016/S0014-5793(02)03399-9. PMID 12417297.
• Banderas-Tarabay JA, Zacarías-D'Oleire IG, Garduño-Estrada R, et al. (2003). "Electrophoretic analysis of whole saliva and prevalence of dental caries. A study in Mexican dental students". Arch. Med. Res. 33 (5): 499–505. doi:10.1016/S0188-4409(02)00395-8. PMID 12459324.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wang H, Tachibana K, Zhang Y, et al. (2003). "Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14". Biochem. Biophys. Res. Commun. 300 (3): 738–44. doi:10.1016/S0006-291X(02)02908-X. PMID 12507512.
• Soares RV, Siqueira CC, Bruno LS, et al. (2003). "MG2 and lactoferrin form a heterotypic complex in salivary secretions". J. Dent. Res. 82 (6): 471–5. doi:10.1177/154405910308200613. PMID 12766201.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ge J, Catt DM, Gregory RL (2004). "Streptococcus mutans surface alpha-enolase binds salivary mucin MG2 and human plasminogen". Infect. Immun. 72 (11): 6748–52. doi:10.1128/IAI.72.11.6748-6752.2004. PMC 523000. PMID 15501816.
• Grys TE, Siegel MB, Lathem WW, Welch RA (2005). "The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells". Infect. Immun. 73 (3): 1295–303. doi:10.1128/IAI.73.3.1295-1303.2005. PMC 1064933. PMID 15731026.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Bruno LS, Li X, Wang L, et al. (2005). "Two-hybrid analysis of human salivary mucin MUC7 interactions". Biochim. Biophys. Acta 1746 (1): 65–72. doi:10.1016/j.bbamcr.2005.08.007. PMID 16203048.
• Li S, Intini G, Bobek LA (2006). "Modulation of MUC7 mucin expression by exogenous factors in airway cells in vitro and in vivo". Am. J. Respir. Cell Mol. Biol. 35 (1): 95–102. doi:10.1165/rcmb.2005-0305OC. PMC 2658701. PMID 16514118.