Mannan 1,2-(1,3)-a-mannosidase

Mannan 1,2-(1,3)-alpha-mannosidase (EC 3.2.1.77, exo-1,2-1,3-alpha-mannosidase, 1,2-1,3-alpha-D-mannan mannohydrolase) is an enzyme with systematic name (1->2)-(1->3)-alpha-D-mannan mannohydrolase.^[1]^[2] This enzyme catalyses the following chemical reaction

Hydrolysis of (1->2)- and (1->3)-linkages in yeast mannan, releasing mannose

A 1,6-alpha-D-mannan backbone remains after action on yeast mannan.

References

↑ Jones, G.H. and Ballou, C.E. (1969). "Studies on the structure of yeast mannan. I. Purification and some properties of an α-mannosidase from an Arthrobacter species". J. Biol. Chem. 244: 1043–1051. PMID 5769177.
↑ Jones, G.H. and Ballou, C.E. (1969). "Studies on the structure of yeast mannan. II. Mode of action of the Arthrobacter α-mannosidase on yeast mannan". J. Biol. Chem. 244: 1052–1059. PMID 5814027.

External links

Mannan 1,2-(1,3)-alpha-mannosidase at the US National Library of Medicine Medical Subject Headings (MeSH)

Hydrolase: sugar hydrolases (EC 3.2)

3.2.1: Glycoside hydrolases

Disaccharidase	Sucrase/Sucrase-isomaltase/Invertase Maltase Trehalase Lactase

Glucosidases	Cellulase Alpha-glucosidase Acid Neutral AB Neutral C Beta-glucosidase cytosolic Debranching enzyme

Other	Amylase Alpha-amylase Chitinase Lysozyme Neuraminidase NEU1 NEU2 NEU3 NEU4 Bacterial neuraminidase Viral neuraminidase Galactosidases Alpha Beta alpha-Mannosidase Glucuronidase Hyaluronidase Pullulanase Glucosylceramidase lysosomal non-lysosomal Galactosylceramidase Alpha-N-acetylgalactosaminidase NAGA Alpha-N-acetylglucosaminidase Fucosidase Hexosaminidase HEXA HEXB Iduronidase Maltase-glucoamylase Heparanase HPSE2

3.2.2: Hydrolysing
N-Glycosyl compounds

DNA glycosylases: Oxoguanine glycosylase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

This article is issued from Wikipedia - version of the Thursday, March 31, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.