RPS24

Ribosomal protein S24
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 4V6X​, 5AJ0​
Identifiers
Symbols	RPS24 ; DBA3; S24
External IDs	OMIM: 602412 MGI: 3645112 HomoloGene: 68148 GeneCards: RPS24 Gene
Gene ontology Molecular function • nucleotide binding • structural constituent of ribosome • translation initiation factor binding • poly(A) RNA binding Cellular component • nucleus • cytoplasm • cytosol • small ribosomal subunit • membrane • cytosolic small ribosomal subunit Biological process • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) • rRNA processing • translation • translational initiation • translational elongation • translational termination • SRP-dependent cotranslational protein targeting to membrane • gene expression • viral process • viral life cycle • viral transcription • erythrocyte homeostasis • ribosomal small subunit biogenesis • cellular protein metabolic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6229	20088
Ensembl	ENSG00000138326	ENSMUSG00000025290
UniProt	P62847	P62849
RefSeq (mRNA)	NM_001026	NM_011297
RefSeq (protein)	NP_001017	NP_035427
Location (UCSC)	Chr 10: 78.03 – 78.06 Mb	Chr 14: 24.49 – 24.5 Mb
PubMed search

40S ribosomal protein S24 is a protein that in humans is encoded by the RPS24 gene.^[1][2][3]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S24E family of ribosomal proteins. It is located in the cytoplasm. Alternative splice variants that encode different protein isoforms exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[3]

References

1. Jones AM, Marzella R, Rocchi M, Hewitt JE (Mar 1997). "Mapping of the human ribosomal small subunit protein gene RPS24 to the chromosome 10q22-q23 boundary". Genomics 39 (1): 121–2. doi:10.1006/geno.1996.4442. PMID 9027498.
2. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
3. "Entrez Gene: RPS24 ribosomal protein S24".

Further reading

• Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID 8722009.
• Huang RT, Li DR, Wei J, et al. (1992). "Isolation and identification of hepatitis E virus in Xinjiang, China". J. Gen. Virol. 73 ( Pt 5) (5): 1143–8. doi:10.1099/0022-1317-73-5-1143. PMID 1588318.
• Brown SJ, Jewell A, Maki CG, Roufa DJ (1990). "A cDNA encoding human ribosomal protein S24". Gene 91 (2): 293–6. doi:10.1016/0378-1119(90)90103-X. PMID 2210388.
• Xu WB, Roufa DJ (1996). "The gene encoding human ribosomal protein S24 and tissue-specific expression of differentially spliced mRNAs". Gene 169 (2): 257–62. doi:10.1016/0378-1119(96)88652-5. PMID 8647458.
• Vladimirov SN, Ivanov AV, Karpova GG, et al. (1996). "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry". Eur. J. Biochem. 239 (1): 144–9. doi:10.1111/j.1432-1033.1996.0144u.x. PMID 8706699.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Yu Y, Ji H, Doudna JA, Leary JA (2005). "Mass spectrometric analysis of the human 40S ribosomal subunit: Native and HCV IRES-bound complexes". Protein Sci. 14 (6): 1438–46. doi:10.1110/ps.041293005. PMC 2253395. PMID 15883184.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.