Sulfadiazine

Sulfadiazine
Systematic (IUPAC) name
4-amino-N-pyrimidin- 2-yl-benzenesulfonamide
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a682130
Pregnancy
category
  • ?
Legal status
  • ℞ (Prescription only)
Routes of
administration		 Topical cream, oral
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Biological half-life ?
Excretion ?
Identifiers
CAS Number 68-35-9 YesY
ATC code J01EC02 QJ01EQ10
PubChem CID 5215
DrugBank DB00359 N
ChemSpider 5026 N
UNII 0N7609K889 N
KEGG D00587 YesY
ChEMBL CHEMBL439 N
Chemical data
Formula C10H10N4O2S
Molar mass 250.278 g/mol
Physical data
Melting point 252 to 256 °C (486 to 493 °F)
 NYesY (what is this?)  (verify)

Sulfadiazine is a sulfonamide antibiotic.

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.[1]

Medical uses

It eliminates bacteria that cause infections by stopping the production of folate inside the bacterial cell, and is commonly used to treat urinary tract infections, and burns.

In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii.

Side effects

Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.

Brand names

Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid

See also

References

  1. ↑ "WHO Model List of EssentialMedicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014.
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