Unsaturated rhamnogalacturonyl hydrolase

Unsaturated rhamnogalacturonyl hydrolase
Identifiers
EC number	3.2.1.172
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Unsaturated rhamnogalacturonyl hydrolase (EC 3.2.1.172, YteR, YesR) is an enzyme with systematic name 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose hydrolase.^[1][2][3] This enzyme catalyses the following chemical reaction

2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose + H₂O $\rightleftharpoons$ 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose

The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168.

References

1. Itoh, T., Ochiai, A., Mikami, B., Hashimoto, W. and Murata, K. (2006). "A novel glycoside hydrolase family 105: the structure of family 105 unsaturated rhamnogalacturonyl hydrolase complexed with a disaccharide in comparison with family 88 enzyme complexed with the disaccharide". J. Mol. Biol. 360: 573–585. doi:10.1016/j.jmb.2006.04.047. PMID 16781735.
2. Zhang, R., Minh, T., Lezondra, L., Korolev, S., Moy, S.F., Collart, F. and Joachimiak, A. (2005). "1.6 Å crystal structure of YteR protein from Bacillus subtilis, a predicted lyase". Proteins 60: 561–565. doi:10.1002/prot.20410. PMID 15906318.
3. Itoh, T., Ochiai, A., Mikami, B., Hashimoto, W. and Murata, K. (2006). "Structure of unsaturated rhamnogalacturonyl hydrolase complexed with substrate". Biochem. Biophys. Res. Commun. 347: 1021–1029. doi:10.1016/j.bbrc.2006.07.034. PMID 16870154.

External links

• Unsaturated rhamnogalacturonyl hydrolase at the US National Library of Medicine Medical Subject Headings (MeSH)