Glycyrrhizinate beta-glucuronidase

glycyrrhizinate beta-glucuronidase
Identifiers
EC number	3.2.1.128
CAS number	102484-56-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a glycyrrhizinate beta-glucuronidase (EC 3.2.1.128) is an enzyme that catalyzes the chemical reaction

glycyrrhizinate + H₂O $\rightleftharpoons$ 1,2-beta-D-glucuronosyl-D-glucuronate + glycyrrhetinate

Thus, the two substrates of this enzyme are glycyrrhizinate and H₂O, whereas its two products are 1,2-beta-D-glucuronosyl-D-glucuronate and glycyrrhetinate.

This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is glycyrrhizinate glucuronosylhydrolase. Other names in common use include glycyrrhizin beta-hydrolase, glycyrrhizin hydrolase, and glycyrrhizinic acid hydrolase.

See also

• Alpha-glucuronidase
• Beta-glucuronidase
• Glucuronosyl-disulfoglucosamine glucuronidase

References

• Muro, T, Kuramoto T, Imoto K and Okada S (1986). "Purification and some properties of glycyrrhizinic acid hydrolase from Aspergillus niger GRM3". Agric. Biol. Chem. 50 (3): 687–692. doi:10.1271/bbb1961.50.687.