DNAJB4

DnaJ (Hsp40) homolog, subfamily B, member 4
Identifiers
Symbols	DNAJB4 ; DNAJW; DjB4; HLJ1
External IDs	OMIM: 611327 MGI: 1914285 HomoloGene: 100610 GeneCards: DNAJB4 Gene
Gene ontology Molecular function • protein binding • unfolded protein binding • chaperone binding Cellular component • nucleoplasm • cytoplasm • cytosol • plasma membrane • extracellular exosome Biological process • protein folding • response to unfolded protein • response to heat Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11080	67035
Ensembl	ENSG00000162616	ENSMUSG00000028035
UniProt	Q9UDY4	Q9D832
RefSeq (mRNA)	NM_007034	NM_025926
RefSeq (protein)	NP_008965	NP_080202
Location (UCSC)	Chr 1: 77.98 – 78.02 Mb	Chr 3: 152.18 – 152.21 Mb
PubMed search

DnaJ homolog subfamily B member 4 is a protein that in humans is encoded by the DNAJB4 gene.^[1][2][3]

References

1. Hoe KL, Won M, Chung KS, Jang YJ, Lee SB, Kim DU, Lee JW, Yun JH, Yoo HS (Apr 1998). "Isolation of a new member of DnaJ-like heat shock protein 40 (Hsp40) from human liver". Biochim Biophys Acta 1383 (1): 4–8. doi:10.1016/s0167-4838(97)00207-0. PMID 9546042.
2. Ohtsuka K, Hata M (Jan 2001). "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress Chaperones 5 (2): 98–112. doi:10.1379/1466-1268(2000)005<0098:MHDHCO>2.0.CO;2. ISSN 1466-1268. PMC 312896. PMID 11147971.
3. "Entrez Gene: DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4".

Further reading

• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rush J, Moritz A, Lee KA; et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.
• Borges JC, Fischer H, Craievich AF, Ramos CH (2005). "Low resolution structural study of two human HSP40 chaperones in solution. DJA1 from subfamily A and DJB4 from subfamily B have different quaternary structures". J. Biol. Chem. 280 (14): 13671–81. doi:10.1074/jbc.M408349200. PMID 15661747.
• Wang CC, Tsai MF, Hong TM; et al. (2005). "The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion". Oncogene 24 (25): 4081–93. doi:10.1038/sj.onc.1208573. PMID 15782117.
• Ancevska-Taneva N, Onoprishvili I, Andria ML; et al. (2006). "A member of the heat shock protein 40 family, hlj1, binds to the carboxyl tail of the human mu opioid receptor". Brain Res. 1081 (1): 28–33. doi:10.1016/j.brainres.2006.01.125. PMID 16542645.
• Tsai MF, Wang CC, Chang GC; et al. (2006). "A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma". J. Natl. Cancer Inst. 98 (12): 825–38. doi:10.1093/jnci/djj229. PMID 16788156.