UBE2O

Ubiquitin-conjugating enzyme E2O
Identifiers
Symbols	UBE2O ; E2-230K
External IDs	MGI: 2444266 HomoloGene: 11113 GeneCards: UBE2O Gene
EC number	6.3.2.19
Gene ontology Molecular function • ubiquitin-protein transferase activity • protein binding • ATP binding • ligase activity • ubiquitin protein ligase binding • poly(A) RNA binding • ubiquitin protein ligase activity • ubiquitin conjugating enzyme activity Cellular component • nucleus • nucleoplasm • cytoplasm Biological process • protein monoubiquitination • positive regulation of BMP signaling pathway • retrograde transport, endosome to Golgi • protein K63-linked ubiquitination Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	63893	217342
Ensembl	ENSG00000175931	ENSMUSG00000020802
UniProt	Q9C0C9	Q6ZPJ3
RefSeq (mRNA)	NM_022066	NM_173755
RefSeq (protein)	NP_071349	NP_776116
Location (UCSC)	Chr 17: 76.39 – 76.45 Mb	Chr 11: 116.54 – 116.58 Mb
PubMed search

Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene.^[1][2][3]

References

1. Yokota T, Nagai H, Harada H, Mine N, Terada Y, Fujiwara H, Yabe A, Miyazaki K, Emi M (Apr 2001). "Identification, tissue expression, and chromosomal position of a novel gene encoding human ubiquitin-conjugating enzyme E2-230k". Gene 267 (1): 95–100. doi:10.1016/S0378-1119(01)00407-3. PMID 11311559.
2. Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
3. "Entrez Gene: UBE2O ubiquitin-conjugating enzyme E2O".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Tomsig JL, Snyder SL, Creutz CE (2003). "Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.". J. Biol. Chem. 278 (12): 10048–54. doi:10.1074/jbc.M212632200. PMID 12522145.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Pope SN, Lee IR (2005). "Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin.". J. Steroid Biochem. Mol. Biol. 94 (1-3): 203–8. doi:10.1016/j.jsbmb.2005.01.007. PMID 15862967.