DNAJC7

DnaJ (Hsp40) homolog, subfamily C, member 7
Identifiers
Symbols	DNAJC7 ; DJ11; DJC7; TPR2; TTC2
External IDs	OMIM: 601964 MGI: 1928373 HomoloGene: 68306 GeneCards: DNAJC7 Gene
Gene ontology Molecular function • protein binding • heat shock protein binding Cellular component • nucleoplasm • cytoplasm • cytosol • cytoskeleton • membrane • extracellular exosome Biological process • protein folding • cellular response to heat • chaperone cofactor-dependent protein refolding • regulation of cellular response to heat Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7266	56354
Ensembl	ENSG00000168259	ENSMUSG00000014195
UniProt	Q99615	Q9QYI3
RefSeq (mRNA)	NM_001144766	NM_019795
RefSeq (protein)	NP_001138238	NP_062769
Location (UCSC)	Chr 17: 41.98 – 42.02 Mb	Chr 11: 100.58 – 100.62 Mb
PubMed search

DnaJ homolog subfamily C member 7 is a protein that in humans is encoded by the DNAJC7 gene.^[1][2][3]

Interactions

DNAJC7 has been shown to interact with RAD9A.^[4]

References

1. Murthy AE, Bernards A, Church D, Wasmuth J, Gusella JF (Nov 1996). "Identification and characterization of two novel tetratricopeptide repeat-containing genes". DNA Cell Biol 15 (9): 727–35. doi:10.1089/dna.1996.15.727. PMID 8836031.
2. Ohtsuka K, Hata M (Jan 2001). "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress Chaperones 5 (2): 98–112. doi:10.1379/1466-1268(2000)005<0098:MHDHCO>2.0.CO;2. PMC 312896. PMID 11147971.
3. "Entrez Gene: DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7".
4. Xiang SL, Kumano T, Iwasaki SI, Sun X, Yoshioka K, Yamamoto KC (2001). "The J domain of Tpr2 regulates its interaction with the proapoptotic and cell-cycle checkpoint protein, Rad9". Biochem. Biophys. Res. Commun. 287 (4): 932–40. doi:10.1006/bbrc.2001.5685. PMID 11573955.

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Xiang SL, Kumano T, Iwasaki SI; et al. (2001). "The J domain of Tpr2 regulates its interaction with the proapoptotic and cell-cycle checkpoint protein, Rad9". Biochem. Biophys. Res. Commun. 287 (4): 932–40. doi:10.1006/bbrc.2001.5685. PMID 11573955.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Brychzy A, Rein T, Winklhofer KF; et al. (2003). "Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system". EMBO J. 22 (14): 3613–23. doi:10.1093/emboj/cdg362. PMC 165632. PMID 12853476.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W; et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Rush J, Moritz A, Lee KA; et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Mehrle A, Rosenfelder H, Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.