Oxanamide

Oxanamide

Systematic (IUPAC) name
2-ethyl-3-propyloxirane-2-carboxamide
Identifiers
CAS Number	126-93-2
ATC code	none
PubChem	CID 31365
ChemSpider	29098
Chemical data
Formula	C8H15NO2
Molar mass	157.21 g/mol
SMILES CCCC1C(O1)(CC)C(=O)N
InChI InChI=1S/C8H15NO2/c1-3-5-6-8(4-2,11-6)7(9)10/h6H,3-5H2,1-2H3,(H2,9,10) Key:WBLPIVIXQOFTPQ-UHFFFAOYSA-N
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Oxanamide (Quiactin) is an anxiolytic and muscle relaxant which can produce sedative and hypnotic effects in sufficiently high doses.^[1] An uncontrolled trial on patients treated in a clinical gynecology practice published in 1959 found that oxanamide was efficacious in the treatment of anxiety resulting from premenstrual syndrome, menopause, and various other causes, with minimal sedation or other side effects.^[2]

References

1. Kuhn, WL; Ketteler, HJ; Van Maanen, EF (1960). "Effects of oxanamide on the central nervous system". Proceedings of the Society for Experimental Biology and Medicine 103: 101–3. PMID 14412594.
2. Robert B. Woodhull (1959). "OXANAMIDE—Adjunctive Use of a New Tranquilizer in Gynecology". California Medicine 90 (4): 275–7. PMC 1577644. PMID 13638840.