Sulconazole

Sulconazole

Systematic (IUPAC) name
1-(2-{[(4-Chlorophenyl)methyl]sulfanyl}-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
Clinical data
Trade names	Exelderm
AHFS/Drugs.com	monograph
MedlinePlus	a698018
Routes of administration	Topical
Identifiers
CAS Number	61318-90-9
ATC code	D01AC09 (WHO)
PubChem	CID 5318
ChemSpider	5127
UNII	5D9HAA5Q5S
KEGG	D08535
ChEBI	CHEBI:9325
ChEMBL	CHEMBL1221
Chemical data
Formula	C18H15Cl3N2S
Molar mass	397.749 g/mol
SMILES Clc1ccc(c(Cl)c1)C(SCc2ccc(Cl)cc2)Cn3ccnc3
InChI InChI=1S/C18H15Cl3N2S/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2 Key:AFNXATANNDIXLG-UHFFFAOYSA-N
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Sulconazole (trade name Exelderm) is an antifungal medication of the imidazole class. It is available as a cream or solution to treat skin infections such as athlete's foot, ringworm, jock itch, and sun fungus.^[1][2] Although not used commercially for insect control, sulconazole nitrate exhibits a strong anti-feeding effect on the keratin-digesting Australian carpet beetle larvae Anthrenocerus australis.^[3]

References

1. Drugs.com: sulconazole topical
2. Fromtling, R. A. (1988). "Overview of medically important antifungal azole derivatives". Clinical Microbiology Reviews 1 (2): 187–217. PMC 358042. PMID 3069196.
3. Sunderland, M. R.; Cruickshank, R. H.; Leighs, S. J. (2014). “The efficacy of antifungal azole and antiprotozoal compounds in protection of wool from keratin-digesting insect larvae”. Textile Research Journal 84 (9): 924–931. http://trj.sagepub.com/content/84/9/924