Tribromometacresol

Tribromometacresol
Systematic (IUPAC) name

2,4,6-Tribromo-3-methylphenol
Identifiers
CAS Number	4619-74-3
ATC code	D01AE03
PubChem	CID 20737
UNII	Q3Z845166M^Y
Synonyms	Micatex Triphysan Triphysol 2,4,6-Tribromo-m-cresol
Chemical data
Formula	C₇H₅Br₃O
Molar mass	344.83 g/mol
Physical data
Melting point	81.5 to 85.5 °C (178.7 to 185.9 °F)
(verify)

Tribromometacresol is an antifungal.^[1]

References

↑ Zsolnai, Tibor (1960). "Action of new fungicides. I. Phenol derivatives". Biochemical Pharmacology 5: 1–19. doi:10.1016/0006-2952(60)90002-2.

Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles
(lanosterol 14
alpha-demethylase inhibitors)

Imidazoles	Topical: bifonazole^‡ chlormidazole^‡ croconazole^‡ fenticonazole^‡ isoconazole^‡ luliconazole neticonazole^‡ omoconazole^‡ butoconazole clotrimazole^# econazole ketoconazole miconazole^# oxiconazole sertaconazole sulconazole tioconazole

Triazoles	Topical: fluconazole^#, fosfluconazole efinaconazole terconazole Systemic: hexaconazole^‡ isavuconazole fluconazole itraconazole posaconazole voriconazole Unknown: albaconazole^‡

Thiazoles	Topical: abafungin^‡

Polyene antimycotics
(ergosterol binding)

Topical: hamycin^‡
natamycin
nystatin^#
Systemic: amphotericin B^#, hamycin^‡

Allylamines
(squalene monooxygenase
inhibitors)

Topical: amorolfine^‡
butenafine
naftifine
terbinafine
Systemic: terbinafine

β-glucan synthase
inhibitors

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	flucytosine^#

Mitotic inhibitors	griseofulvin^#

Aminoacyl tRNA synthetase inhibitors	tavaborole

Others

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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