2,3-Dichlorophenylpiperazine
This article is about the chemical compound. For the Disease Control Priorities Project, see Disease Control Priorities Project. For the New Jersey child protection agency now called the Division of Child Protection and Permanency, see Division of Youth and Family Services.
Names | |
---|---|
IUPAC name
1-(2,3-dichlorophenyl)piperazine | |
Identifiers | |
41202-77-1 | |
ChemSpider | 744460 |
Jmol interactive 3D | Image |
PubChem | 851833 |
| |
| |
Properties | |
C10H12Cl2N2 | |
Molar mass | 231.12 g/mol |
Appearance | brown oil |
Density | 1.272g/cm3 °C |
Melting point | 242 to 244 °C (468 to 471 °F; 515 to 517 K) |
Boiling point | 365.1 °C (689.2 °F; 638.2 K) at 760mmHg |
Hazards | |
Flash point | 174.6 °C (346.3 °F; 447.8 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound. It is both a precursor in the synthesis of aripiprazole and one of its metabolites.[1][2] It is unknown whether 2,3-DCPP is pharmacologically active similar to its close analogue 3-chlorophenylpiperazine (mCPP).
Chemical derivatives
See also
References
- ↑ Leś A, Badowska-Rosłonek K, Łaszcz M, Kamieńska-Duda A, Baran P, Kaczmarek Ł (2010). "Optimization of aripiprazole synthesis". Acta Poloniae Pharmaceutica 67 (2): 151–7. PMID 20369792.
- ↑ Caccia S (August 2007). "N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed". Current Drug Metabolism 8 (6): 612–22. doi:10.2174/138920007781368908. PMID 17691920.
This article is issued from Wikipedia - version of the Thursday, February 25, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.