DNAJB9

DnaJ (Hsp40) homolog, subfamily B, member 9
PDB rendering based on 2ctr.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2CTR​
Identifiers
Symbols	DNAJB9 ; ERdj4; MDG-1; MDG1; MST049; MSTP049
External IDs	OMIM: 602634 MGI: 1351618 HomoloGene: 32155 GeneCards: DNAJB9 Gene
Gene ontology Molecular function • protein binding • misfolded protein binding Cellular component • nucleolus • cytoplasm • endoplasmic reticulum • endoplasmic reticulum lumen • endoplasmic reticulum membrane • extracellular exosome Biological process • ER-associated ubiquitin-dependent protein catabolic process • endoplasmic reticulum unfolded protein response • IRE1-mediated unfolded protein response • cellular protein metabolic process Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4189	27362
Ensembl	ENSG00000128590	ENSMUSG00000014905
UniProt	Q9UBS3	Q9QYI6
RefSeq (mRNA)	NM_012328	NM_013760
RefSeq (protein)	NP_036460	NP_038788
Location (UCSC)	Chr 7: 108.57 – 108.57 Mb	Chr 12: 44.21 – 44.21 Mb
PubMed search

DnaJ homolog subfamily B member 9 is a protein that in humans is encoded by the DNAJB9 gene.^[1][2][3]

References

1. Prols F, Liehr T, Rinke R, Rautenstrauss B (Apr 1998). "Assignment of the microvascular endothelial differentiation gene 1 (MDG1) to human chromosome band 14q24.2→q24.3 by fluorescence in situ hybridization". Cytogenet Cell Genet 79 (1–2): 149–50. doi:10.1159/000134706. PMID 9533036.
2. Ohtsuka K, Hata M (Jan 2001). "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress Chaperones 5 (2): 98–112. doi:10.1379/1466-1268(2000)005<0098:MHDHCO>2.0.CO;2. PMC 312896. PMID 11147971.
3. "Entrez Gene: DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9".

Further reading

• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Pröls F, Mayer MP, Renner O, et al. (2001). "Upregulation of the cochaperone Mdg1 in endothelial cells is induced by stress and during in vitro angiogenesis". Exp. Cell Res. 269 (1): 42–53. doi:10.1006/excr.2001.5294. PMID 11525638.
• Shen Y, Meunier L, Hendershot LM (2002). "Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress". J. Biol. Chem. 277 (18): 15947–56. doi:10.1074/jbc.M112214200. PMID 11836248.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Berger BJ, Müller TS, Buschmann IR, et al. (2003). "High levels of the molecular chaperone Mdg1/ERdj4 reflect the activation state of endothelial cells". Exp. Cell Res. 290 (1): 82–92. doi:10.1016/S0014-4827(03)00316-1. PMID 14516790.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Lin KT, Lu RM, Tarn WY (2004). "The WW Domain-Containing Proteins Interact with the Early Spliceosome and Participate in Pre-mRNA Splicing In Vivo". Mol. Cell. Biol. 24 (20): 9176–85. doi:10.1128/MCB.24.20.9176-9185.2004. PMC 517884. PMID 15456888.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.