Succinyl-CoA hydrolase

succinyl-CoA hydrolase
Identifiers
EC number 3.1.2.3
CAS number 9025-86-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a succinyl-CoA hydrolase (EC 3.1.2.3) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + H2O \rightleftharpoons CoA + succinate

Thus, the two substrates of this enzyme are succinyl-CoA and H2O, whereas its two products are CoA and succinate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is succinyl-CoA hydrolase. Other names in common use include succinyl-CoA acylase, succinyl coenzyme A hydrolase, and succinyl coenzyme A deacylase. This enzyme participates in citrate cycle (tca cycle).

References

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